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Chromoblastomycosis.

D Vijaya1, B H Kumar

  • 1Bowring and Lady Curzon Hospitals, Bangalore, India. vijayadanand@rediffmail.com

Mycoses
|February 1, 2005
PubMed
Summary
This summary is machine-generated.

A rare fungal infection, chromoblastomycosis, caused by Cladophilalospora sp. was successfully treated with surgery after antifungal medication failed. This case highlights surgical resection as a viable option for recalcitrant chromoblastomycosis.

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Area of Science:

  • Medical Mycology
  • Dermatology

Background:

  • Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissue, primarily affecting tropical and subtropical regions.
  • It is typically caused by dematiaceous fungi from the genera Fonsecaea, Phialophora, and Cladophilalospora.
  • Traumatic inoculation, often through minor skin injuries, is the usual mode of transmission.

Observation:

  • A 70-year-old male agriculturist presented with a year-long history of a painless, verrucous lesion on his left leg.
  • The lesion appeared after abrasion from a coconut tree branch.
  • Potassium hydroxide (KOH) preparation of a skin biopsy revealed fungal elements, and Cladophilalospora sp. was isolated in culture.

Findings:

  • The patient was diagnosed with chromoblastomycosis.

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  • Initial treatment with itraconazole was ineffective.
  • Complete surgical resection of the lesion was performed.

    • Implications:

    • Surgical resection can be an effective treatment for chromoblastomycosis when antifungal therapy fails.
    • Early diagnosis and appropriate management are crucial for successful outcomes in chromoblastomycosis.
    • This case underscores the importance of considering fungal infections in agricultural workers with chronic skin lesions.