Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microwave coagulation therapy in canine peripheral lung tissue.

Kinya Furukawa1, Toyoaki Miura, Yasuhumi Kato

  • 1Department of Thoracic Surgery, Kasumigaura Hospital, Tokyo Medical University, 3-20-1 Chuo Ami-machi, Inashiki-gun, Ibaraki 300-0395, Japan. k-furu@tokyo-med.ac.jp

The Journal of Surgical Research
|February 1, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of 1.1 mm ultrathin cryobiopsy through a guide sheath for sampling of peripheral pulmonary lesions.

Journal of thoracic disease·2026
Same author

National epidemiological survey on pharyngeal, laryngeal, and tracheal stenosis in Japan: A national survey on airway stenosis.

Auris, nasus, larynx·2024
Same author

Rapid growth of primary pulmonary meningioma with hemoptysis.

Oxford medical case reports·2024
Same author

A Prospective Cohort Study Exploring the Effect of Lenvatinib Planned Drug Holidays in Treatment of Differentiated Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association·2024
Same author

Anesthetic management of airway stent placement by rigid bronchoscopy with superior laryngeal nerve block while preserving spontaneous breathing: A case report.

Clinical case reports·2023
Same author

Perianal erosion in a patient with sorafenib-induced hand-foot syndrome: A case report.

The Journal of dermatology·2023

Microwave coagulation therapy (MCT) effectively destroys tissue in canine lungs, creating a 20 mm coagulation zone. This minimally invasive technique shows promise for treating peripheral lung tumors with minimal damage to healthy tissue.

Area of Science:

  • Pulmonary Medicine
  • Surgical Oncology
  • Biomedical Engineering

Background:

  • Development of less invasive local treatments for lung tumors is crucial for patients unsuitable for surgery.
  • Microwave coagulation therapy (MCT), successful in liver tumors, was investigated for lung tissue safety and efficacy.
  • Canine lung tissue was used to assess thermal response, coagulation, and histological changes.

Purpose of the Study:

  • To evaluate the efficacy and safety of microwave coagulation therapy (MCT) in normal canine lung tissue.
  • To determine the thermal spread and coagulation dimensions achieved with MCT in lung tissue.
  • To assess the short-term and long-term histological effects of MCT on lung tissue.

Main Methods:

  • Microwave coagulation therapy was applied to normal canine lung tissue.

Related Experiment Videos

  • Thermal response, coagulation area, and histological examinations were performed.
  • Tissue analysis included collagen fiber, stromal edema, granulation tissue, and scar formation.

    • Main Results:

    • Temperatures reached 90-100°C at 5mm and 70-80°C at 10mm from the electrode.
    • Coagulation area was approximately 20 mm in diameter at 40W and 60W.
    • Histology showed collagen thickening, edema, granulation tissue, and eventual scar formation over 6 months.

    Conclusions:

    • Microwave coagulation therapy (MCT) is a viable option for minimally invasive treatment of peripheral lung tumors.
    • The study demonstrated predictable thermal effects and tissue remodeling following MCT in lung tissue.
    • MCT offers a potentially safer alternative for lung tumor ablation in select patient populations.