Related Experiment Video
Updated: Aug 19, 2026

Neutron Crystallography Data Collection and Processing for Modelling Hydrogen Atoms in Protein Structures
Published on: December 1, 2020
Structure of 2-C-(hydroxymethyl)-D-ribose (hamamelose) in the solid-state analyzed by CP MAS NMR and X-ray
Z Hricovíniová1, D Lamba, M Hricovíni
1Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, SK-84538 Bratislava, Slovakia. chemhric@savba.sk
Abstract:
D-Hamamelose, a branched-chain ribose (2-C-(hydroxymethyl)-D-ribose), has been synthesized and its solid-state structure analyzed by (13)C CP MAS NMR spectra and X-ray data. The presence of the complex pattern of resonances in the anomeric region, as well as in the ring carbon region, in (13)C CP MAS NMR spectrum indicated that the mixture of four cyclic forms, alpha- and beta-furanoses, as well as both alpha- and beta-pyranoses were present in the solid-state. X-ray analysis of crystals showed that D-hamamelose belongs to the monoclinic system with unit cell: a=4.790A, b=8.671A, c=8.880A and beta=98.89 degrees , space group P2(1). The furanose ring has the (2)E conformation.
Related Concept Videos
Determination of Crystal Structures
2D NMR: Homonuclear Correlation Spectroscopy (COSY)
2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)
Nucleic Acid Structure
DNA Structure
DNA has a double-helix structure. The...
X-ray Crystallography
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR

