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Updated: Aug 19, 2026
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Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl4) Exposure Through an Orogastric Tube
Published on: April 28, 2020
Effect of Asteracantha longifolia Nees. against CCl4 induced liver dysfunction in rat
Sunita Shailajan1, Naresh Chandra, R T Sane
1SP Mandali's, Ramnarain Ruia College, Matunga, Mumbai 400 019, India. sunitashailajan@yahoo.co.in
Indian Journal of Experimental Biology
|February 5, 2005
Abstract:
Significant recovery after treatment with the whole plant slurry of A.longifolia Nees. was observed in plasma AST, ALT and cholesterol levels in CCl4 induced hepatotoxic rats. This was amply supported by electron micrographs, which indicated normalization of cytoarchitecture of mitochondria and endoplasmic reticulum. The results suggest that the slurry of the plant is useful as a liver tonic.
