Related Experiment Video
Updated: Aug 10, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
The effect of chorionic villus sampling on fetal heart rate
Shahram Akhlaghpoor1, Taraneh Hosseinipoor
1Novin Medical Radiation Institute, Tehran, Iran. Shahram_ak@yahoo.com
Objective:
Fetal heart rate (FHR) variation during chorionic villus sampling (CVS) is a controversial topic. Limited studies have been published on this subject. Our study intended to evaluate the effects of CVS on the FHR.
Method:
One hundred and sixty-five patients undergoing first-trimester elective CVS for prenatal diagnosis of beta-thalassemia were entered into a prospective study. M-mode FHR was obtained before and immediately after CVS in the patients. Potentially confounding variables also recorded included: gestational age, number of needle passes and placental location.
Results:
FHR values before and after CVS were compared using the paired t test and showed no statistically significant differences by 95% confidence. No differences were found in data analyzing gestational age, number of needle passes or placental location.
Conclusion:
We were unable to detect any significant change in FHR after performing CVS. It seems that FHR is generally not altered by CVS.

