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Updated: Aug 19, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
Amyotrophic lateral sclerosis and sports: a case-control study
M Valenti1, F E Pontieri, F Conti
1Section of Medical Statistics and Epidemiology, Faculty of Human Movement and Sports Science, University of L'Aquila, L'Aquila, Italy. valenti@cc.univaq.it
Abstract:
An increased incidence of amyotrophic lateral sclerosis (ALS) amongst soccer players in Italy has recently been reported. A case-control study (300 cases and 300 matched controls) was conducted to explore the association between ALS and physical/sports activities, with specific reference to trauma-related risk. Neither the practice of competitive sports nor sports-related traumas were found to be associated with an increased risk of ALS. The practice of physical activities or sports is not per se a risk factor for ALS. Our results exclude sports-related microtraumas as etiopathogenic factors in the natural history of ALS.
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