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Topiramate for binge eating disorder
Cristina De Bernardi1, Silvia Ferraris, Pierluigi D'Innella
1Department of Psychiatry, University of Eastern Piedmont, Novara, Italy.
Progress in Neuro-Psychopharmacology & Biological Psychiatry
|February 8, 2005
Summary
Topiramate, an anti-convulsant, effectively treated a patient with binge eating disorder. This medication also reduces hunger, aiding in weight loss for individuals unresponsive to other therapies.
Area of Science:
- Neuroscience
- Pharmacology
- Psychiatry
Background:
- Topiramate is an anti-convulsant medication.
- It modulates voltage-activated sodium channels and glutamate and GABA receptors.
- Topiramate has demonstrated effects on appetite regulation and weight reduction.
Observation:
- A patient with binge eating disorder (BED) was evaluated.
- The patient had not responded to multiple prior treatment regimens.
- The patient presented with symptoms of BED and a desire for weight management.
Findings:
- Topiramate treatment resulted in successful management of binge eating episodes.
- The patient experienced significant weight loss during the course of treatment.
- The anti-convulsant properties of topiramate were leveraged for psychiatric treatment.
Implications:
- Topiramate presents a potential therapeutic option for treatment-resistant binge eating disorder.
- The dual action of topiramate on neurological pathways and appetite may be beneficial in complex cases.
- Further research into topiramate for eating disorders is warranted.