Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current concepts in lymphatic malformation.

B B Lee1, Y W Kim, J M Seo

  • 1Department of Surgery, Sungkyunkwan University School of Medicine and Samsung Medical Center, Seoul, Korea. bblee38@comcast.net

Vascular and Endovascular Surgery
|February 8, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autonomous surface sampling for the Europa Lander mission concept.

Science robotics·2025
Same author

Low-dose CT angiography of the lower extremities: a comparison study of image quality and radiation dose.

Clinical radiology·2020
Same author

Abdominal Functional Electrical Stimulation to Augment Respiratory Function in Spinal Cord Injury.

Topics in spinal cord injury rehabilitation·2019
Same author

Initial Experience With Hand-Assisted Laparoscopic Living Donor Nephrectomy: Training and Clinical Practice as a General Surgeon.

Transplantation proceedings·2018
Same author

Designing a magnesium alloy with high strength and high formability.

Nature communications·2018
Same author

Percutaneous stent placement for malignant hilar biliary obstruction: a comparison between criss-cross and T-configuration techniques.

Clinical radiology·2017
Same journal

Abdominal Aortic Aneurysm SAC Embolization Passing Through an Aortocaval Fistula.

Vascular and endovascular surgery·2026
Same journal

Hybrid Lower Extremity Revascularization Avoiding Groin Re-Exploration in a Morbidly Obese Patient With Acute Limb Ischemia After Failed Femoral-Popliteal PTFE Bypass: A Case Report and Literature Review.

Vascular and endovascular surgery·2026
Same journal

A Large Superior Gluteal Artery Pseudoaneurysm Masquerading as a Pelvic Mass: When Not to Biopsy.

Vascular and endovascular surgery·2026
Same journal

Total Laparoscopic Inferior Mesenteric Artery Clipping for Persistent Type II Endoleak Following EVAR: A Case Report and Review of Surgical Strategy.

Vascular and endovascular surgery·2026
Same journal

Predictors for Type 2 Endoleak Requiring Embolization: Large Inferior Mesenteric Artery, Multiple Lumbar Arteries, and Anticoagulation.

Vascular and endovascular surgery·2026
Same journal

Diagnosis and Treatment Strategies for Femoral Vein Extramembranous Cysts: A Case Analysis and Literature Review.

Vascular and endovascular surgery·2026
See all related articles

Lymphatic malformations (LMs) are classified into truncular (T) and extratruncular (ET) forms. Management strategies vary, with complex decongestive physiotherapy for T-forms and sclerotherapy for ET-forms, emphasizing patient compliance for optimal outcomes.

Area of Science:

  • Vascular Surgery
  • Pediatric Surgery
  • Genetics

Background:

  • Lymphatic malformations (LMs) are common congenital vascular malformations (CVMs).
  • The Hamburg classification distinguishes truncular (T) and extratruncular (ET) forms of LMs, arising from lymphangiogenesis defects.
  • Understanding management outcomes for both LM forms is crucial.

Purpose of the Study:

  • To evaluate the current management results for truncular (T) and extratruncular (ET) forms of lymphatic malformations (LMs).

Main Methods:

  • Retrospective review of clinical data from 315 LM patients treated between 1994 and 2001.
  • Lymphoscintigraphy as a primary diagnostic tool.
  • Treatment modalities included sclerotherapy (OK-432, ethanol) for ET-LMs and complex decongestive physiotherapy (CDP) +/- surgery for T-LMs.

Related Experiment Videos

Main Results:

  • ET-LMs (89 patients) were often cystic and located in the head/neck/thorax, treated effectively with sclerotherapy (OK-432 yielded excellent results in 88.9% of cystic types).
  • T-LMs (226 patients) involved aplasia/obstruction, predominantly in extremities, with CDP showing good response in early stages (I-II) but diminishing in later stages (III-IV).
  • Surgical intervention for T-LMs had limited success, largely due to poor patient compliance, which was critical for long-term outcomes in both forms.

Conclusions:

  • Primary lymphedema (T-LM) management is effective with CDP and compressotherapy, with surgical options beneficial for compliant patients.
  • ET-LMs, especially cystic types, respond well to sclerotherapy using less toxic agents.
  • A multidisciplinary team approach is essential for optimal LM patient care.