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Primary progressive aphasia: reversed asymmetry of atrophy and right hemisphere language dominance
M Mesulam1, S Weintraub, T Parrish
1Cognitive Neurology and Alzheimer's Disease Center and the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. mmesulam@northwestern.edu
Abstract:
Primary progressive aphasia (PPA) is almost always associated with asymmetrical left hemisphere degeneration. The authors report that right hemisphere atrophy in a patient with PPA was associated with atypical right hemisphere dominance for language. This suggests that neuronal damage in PPA is therefore tightly linked to the underlying anatomy of the language network.
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