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Related Experiment Videos

Fever therapy revisited.

U Hobohm1

  • 1University of Applied Sciences, Bioinformatics, Wiesenstrasse 14, D-35390 Giessen, Germany. uwe.hobohm2tg.fh-giessen.de

British Journal of Cancer
|February 9, 2005
PubMed
Summary
This summary is machine-generated.

Spontaneous cancer regression, though rare, is often linked to severe infections. This review explores feverish infections as a potential trigger for cancer remission, examining epidemiological and immunological data.

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Area of Science:

  • Oncology
  • Immunology
  • Infectious Diseases

Background:

  • Spontaneous cancer regression and remission are documented phenomena.
  • The triggers and causes remain largely unelucidated, with limited experimental evidence.
  • Existing literature suggests a potential link between infections and spontaneous cancer remission.

Purpose of the Study:

  • To review and summarize existing literature on spontaneous cancer regression.
  • To discuss potential causes and triggers, with a focus on infections.
  • To evaluate the role of feverish infections as a putative trigger for cancer remission.

Main Methods:

  • Literature survey and summarization of published cases and studies.
  • Analysis of epidemiological and immunological evidence.

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  • Discussion of potential mechanisms linking infection and cancer regression.

    • Main Results:

    • A significant fraction of spontaneous cancer regression cases are associated with severe, feverish infections.
    • Infections are investigated as a potential trigger for spontaneous remission.
    • Epidemiological and immunological data are considered in evaluating this link.

    Conclusions:

    • Feverish infections represent a plausible trigger for spontaneous cancer regression.
    • Further research into the immunological mechanisms is warranted.
    • Fever therapy is proposed as a potential future application for cancer treatment.