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Updated: Aug 19, 2026
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Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments
Published on: January 23, 2018
Selective polymorph transformation via solvent-drop grinding
Andrew V Trask1, Ning Shan, W D Samuel Motherwell
1Pfizer Institute for Pharmaceutical Materials Science, Department of Chemistry, University of Cambridge, UK.
Chemical Communications (Cambridge, England)
|February 9, 2005
Abstract:
A method of inducing specific polymorph transformations is exemplified with two single-component systems, whereby a given crystal form undergoes conversion when subjected to solid state grinding in the presence of a minor quantity of a certain solvent.
