Characterization of reactive and suppressive cells in the mouse embryonic liver by peanut agglutinin (PNA)

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Embryonic liver cells suppressed the MLC response of adult mouse spleen cells and reactivity to mitogens Con A, PHA and LPS. Suppression was exerted by cells agglutinated by PNA (PNA+ cells). Cells reacting to LPS and to DxS were found in the nonagglutinated (PNA-) cell fraction. The PNA+ fraction did not react to DxS nor did it reduce the response of sdult spleen cells to this mitogen.

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