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Bovine submandibular gland extracts interact with the human hemostasis factors
G Menghi1, D Piciotti, F Ravaglia
1Dipartimento di Biologia M.C.A., Università di Camerino, Italy.
Cellular and Molecular Biology
|April 1, 1992
Abstract:
Glycoconjugates were extracted from the bovine submandibular gland and their anticoagulant activity was tested on the blood coagulation of human beings. The methods employed demonstrated that the thromboelastographic parameters were only modified by the highest concentration of glycoconjugates. Activated Partial Thromboplastin Time (aPTT) and Thrombin Time (TT) were affected by dose-coupling response. Prothrombin Time (PT) and Reptilase Time (RT) were not modified.