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[Studies on chemical constituents in fruit of Rubus chingii]
1Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100094, China.
Objective:
To study the chemical constituents of the fruit of Rubus chingii.
Method:
The compounds were isolated and purified by recrystallization and chromatography with silica gel column and Sephadex LH-20 column. Their structures were identified by physicochemical properties and spectral analysis.
Result:
Eleven compounds were isolated as oleanic acid (I), ursolic acid (II), maslinic acid (III), 2alpha-hydroxyursolic acid (IV), arjunic acid (V), hexacosyl p-coumarate (VI), tiliroside (VII), stearic acid (VIII), lacceroic acid (IX), beta-sitosterol (X), daucosterol (XI).
Conclusion:
Compounds I, II, III, IV, V, VI, VIII, IX, XI were isolated from R. chingii for the first time.
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