Related Experiment Video
Updated: Jul 28, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
Permanent pacing is a risk factor for the development of heart failure
Ronald S Freudenberger1, Alan C Wilson, Janet Lawrence-Nelson
1Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA. freuders@umdnj.edu
Abstract:
No previous study has examined the importance of right ventricular pacing as a risk factor for the development of heart failure (HF) in subjects without a history of HF. A cohort study of patients who underwent initial pacemaker implantation (n = 11,426) was conducted to test the hypothesis that patients with ventricular dyssynchrony created by permanent pacing would develop HF, as shown by new HF hospitalizations or HF-related deaths, at a higher rate than matched controls.
Related Concept Videos
Pathophysiology of Heart Failure
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Mitral Regurgitation I: Introduction
Pericarditis IV: Nursing Management
Heart Failure I: Introduction
Heart Failure II: Pathophysiology

