Extrarenal Wilms' tumor of the uterine corpus
J McAlpine1, M Azodi, D O'Malley
1Department of Obstetrics and Gynecology, Yale University School of Medicine, 333 Cedar St., New Haven, CT 06510, USA. mcalpine_j@yahoo.com
Background:
Extrarenal Wilms' tumors (EWT) are rare. In the female genital tract, only 15 cases (6 adults, 9 children) of EWT have been reported. A case of uterine Wilms' tumor in an adult is presented with a review of the literature.
Case:
A 44-year-old woman presented with a bleeding polypoid cervical mass. Biopsy revealed EWT. She was surgically staged, received chemotherapy, and is without evidence of disease at 1 year follow-up.
Conclusions:
Prognosis and treatment of EWT may differ by location and patient age. Literature review of uterine Wilms' tumor reveals favorable outcome with (1) focal disease confined to the uterus and (2) adequate surgery, including hysterectomy. The National Wilms' Tumor Study Group recommends adjuvant chemotherapy for all EWT. Radiation may be reserved for patients with residual, metastatic and/or recurrent disease.
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