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Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Gastroesophageal reflux and respiratory disorders
1Division of Immunology and Allergy, Texas Tech Regional Academic Health Science Center, El Paso 79902.
Comprehensive Therapy
|March 1, 1992
Summary
Gastroesophageal reflux (GER) is a frequent cause of chronic respiratory issues, particularly asthma. Recognizing and treating GER can significantly improve respiratory symptoms, especially in difficult-to-control asthma cases.
Area of Science:
- Pulmonology
- Gastroenterology
Background:
- Gastroesophageal reflux (GER) is a significant factor in chronic respiratory diseases.
- A notable and frequent association exists between asthma and GER.
Purpose of the Study:
- To highlight the bidirectional relationship between asthma and GER.
- To inform clinicians about considering GER in patients with unexplained or worsening respiratory conditions, especially asthma.
Main Methods:
- Observational analysis of the relationship between GER and respiratory diseases.
- Clinical awareness and diagnostic consideration of GER in specific patient populations.
Main Results:
- Asthma can exacerbate GER, and GER can trigger asthma symptoms.
- Patients with asthma uncontrolled by standard treatments or requiring systemic steroids are often suspected of having GER-provoked issues.
Conclusions:
- Clinicians must consider GER in patients with worsening respiratory status without clear causes.
- Effective recognition and management of GER frequently lead to substantial improvements in respiratory conditions, sometimes dramatically.
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