Related Experiment Video
Updated: Aug 19, 2026
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
Interferometric technique to measure biomechanical changes in the cornea induced by refractive surgery
Philip David Jaycock1, Leon Lobo, Jamal Ibrahim
1Department of Ophthalmology, Rayne Institute, St. Thomas' Hospital, London, United Kingdom. philipjaycock@hotmail.com
Purpose:
To develop a technique to quantify biomechanical changes in the cornea after microkeratome incisions as would be performed in laser in situ keratomileusis.
Setting:
St Thomas' Hospital, London, and the Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Loughborough, United Kingdom.
Methods:
Corneal displacements of whole sheep eyes were studied under hydrostatic loading using electronic speckle pattern interferometry before and after microkeratome incisions.
Results:
After hydrostatic loading, there was a 20.7% increase in corneal displacement in corneas with microkeratome incisions compared to unoperated corneas; this was statistically significant (P=.0068, unpaired t test).
Conclusions:
Results show that in the formation of the microkeratome flap, collagen fibers are severed and minimal biomechanical loading is distributed through the flap. Corneal biomechanical integrity is compromised after microkeratome incisions.
