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[Atrial septal defect associated with mitral valve prolapse--prevalence and clinical significance]

Elzbieta Suchoń1, Piotr Podolec, Wojciech Płazak

  • 1Klinika Chorób Serca i Naczyń, Instytutu Kardiologii Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie. esuchon@szpitaljp2.krakow.pl

Przeglad Lekarski
|February 24, 2005
PubMed
Abstract

Insights

Mitral valve prolapse (MVP) is a functional disorder in patients with atrial septal defect (ASD), stemming from the atrial shunt. This condition does not impact the cardiopulmonary capacity of individuals with ASD.

Area of Science:

  • Cardiology
  • Echocardiography
  • Exercise Physiology

Background:

  • Atrial septal defect (ASD) is often associated with mitral valve prolapse (MVP).
  • Understanding the prevalence and clinical significance of MVP in ASD patients is crucial.

Purpose of the Study:

  • To evaluate the prevalence, etiology, and clinical significance of mitral valve prolapse (MVP) in patients with atrial septal defect (ASD).

Main Methods:

  • Echocardiography was used to diagnose MVP in 47 patients with secundum ASD.
  • Patients underwent exercise testing to assess cardiopulmonary capacity.
  • The study population was divided into groups with and without MVP.

Main Results:

  • Mitral valve prolapse (MVP) was identified in 36% of patients with atrial septal defect (ASD).
  • MVP was not linked to significant mitral regurgitation or reduced cardiopulmonary capacity.
  • Higher pulmonary to systemic flow ratio (Qp/Qs) and lower left to right ventricle ratio (LV/RV) were observed in the MVP group.

Conclusions:

  • Mitral valve prolapse (MVP) in atrial septal defect (ASD) patients is considered a functional disorder.
  • The atrial shunt and interventricular septum shift are implicated in the etiology of MVP in ASD.
  • MVP does not negatively affect the exercise capacity or cardiopulmonary function in individuals with ASD.

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