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Related Experiment Videos

Caries and fluoride processes.

G S Ingram1, E A Agalamanyi, S M Higham

  • 1Cariology Research Group, Department of Clinical Dental Sciences, School of Dentistry, University of Liverpool, Edwards Building, Daulby Street, Liverpool L69 3GN, UK.

Journal of Dentistry
|February 24, 2005
PubMed
Summary
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Salivary fluoride levels, though low, interact with tooth minerals, promoting crystal growth and calcium uptake. These findings suggest low fluoride uptake can impact tooth remineralization, not just high levels.

Area of Science:

  • Biomineralization
  • Dental Research
  • Fluoride Chemistry

Background:

  • Salivary fluoride is crucial for dental health.
  • Understanding fluoride's interaction with tooth mineral is key to preventing caries.
  • The role of low salivary fluoride levels in remineralization requires further investigation.

Purpose of the Study:

  • To determine salivary fluoride levels and their sources.
  • To investigate the interaction between salivary fluoride and tooth mineral (hydroxyapatite).
  • To assess the effect of salivary fluoride on calcium re-acquisition and tooth remineralization.

Main Methods:

  • Fluoride, calcium, and phosphate levels were quantified using electrode, complexometric titration, and colorimetry, respectively.
  • Salivary fluoride uptake by hydroxyapatite mineral was measured.

Related Experiment Videos

  • The impact of low fluoride levels on calcium and phosphate in solution with mineral suspensions was analyzed.

    • Main Results:

    • Low salivary fluoride levels were detected but demonstrated interaction with hydroxyapatite.
    • These fluoride levels induced apatite crystallite growth.
    • Calcium-deficient apatite showed preferential calcium acquisition in the presence of fluoride.

    Conclusions:

    • Salivary fluoride levels correlate with water fluoride content and are acquired by hydroxyapatite.
    • Topical fluoride is retained on oral tissues.
    • Even low fluoride concentrations promote mineral crystallite growth and preferential calcium uptake.
    • These effects occur at low fluoride uptakes, questioning the reliance on high fluoride uptake as a sole indicator of caries reduction.