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Updated: Jul 31, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Hepatitis B vaccination and central nervous system demyelination: an immunological approach
E Piaggio1, A Ben Younes, S Desbois
1INSERM U563, Purpan University Hospital, Place Dr Baylac, Toulouse 31000, France.
Abstract:
Demyelination events or multiple sclerosis following hepatitis B virus (HBV) vaccination have been reported. We therefore compared the T-cell response to HBsAg in patients with CNS demyelination following HBV vaccination and in HBV-vaccinated healthy individuals. Our data showed no differences in terms of T-cell proliferation or cytokine production between these groups and may help to allay concerns that HBV vaccination might trigger a deleterious immune response.
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