Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mesodermal adenosarcoma of the testis.

Ranleigh L Fleshman1, Jay K Wasman, Donald G Bodner

  • 1Department of Pathology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH 44106, USA.

The American Journal of Surgical Pathology
|February 24, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microbial Differences in Prostate Lesions Between Black and White American Men.

The Prostate·2026
Same author

Proteome-Based Plasma Biomarkers for Cognitive Dysfunction in an Androgen Deprivation Model.

Molecular neurobiology·2025
Same author

miRNAs Regulating GSTP1 as Potential Diagnostic Biomarkers in Prostate Cancer.

The Prostate·2025
Same author

Clear Cell Renal Cell Carcinoma: A Comprehensive Review of its Histopathology, Genetics, and Differential Diagnosis.

International journal of surgical pathology·2024
Same author

Early Bone Metastases are Associated with Worse Outcomes in Metastatic Urothelial Carcinoma.

Bladder cancer (Amsterdam, Netherlands)·2024
Same author

Multi-scale statistical deformation based co-registration of prostate MRI and post-surgical whole mount histopathology.

Medical physics·2023
Same journal

NF2/Merlin Immunohistochemistry Helps Distinguish Collecting Duct Carcinoma From Upper Tract Urothelial Carcinoma.

The American journal of surgical pathology·2026
Same journal

Neuroendocrine Carcinoma of the Gallbladder: Clinicopathologic and Immunohistochemical Analysis of 31 Cases.

The American journal of surgical pathology·2026
Same journal

Papillary Renal Neoplasm With Reverse Polarity Is a Distinct Distal Nephron-Derived Tumor With Unique Methylation Profile.

The American journal of surgical pathology·2026
Same journal

Biallelic ARID1A Alterations: A Promising Novel Biomarker for Risk Stratification and Management in Pediatric Malignant Hepatocellular Tumors.

The American journal of surgical pathology·2026
Same journal

Absent Cyclin D1 Expression in Myeloid Sarcomas Distinguishes From Malignant Histiocytic Neoplasms: When Morphologic Ambiguity is Deceptive.

The American journal of surgical pathology·2026
Same journal

Clinicopathologic Study of 39 Mismatch Repair-deficient Sarcomas Demonstrates Recurrent Histologic Patterns and Supports Universal Screening of Pleomorphic Rhabdomyosarcoma, Uterine Leiomyosarcoma, and Undifferentiated and Unclassified Sarcomas.

The American journal of surgical pathology·2026
See all related articles

This study describes the first reported case of mesodermal adenosarcoma in the testis. This biphasic neoplasm, typically found in the uterus, presented as a complex testicular tumor in a 76-year-old male patient.

Area of Science:

  • Oncology
  • Pathology
  • Urologic Oncology

Background:

  • Biphasic neoplasms with benign epithelial and malignant stromal components, known as adenosarcomas, are well-documented in the uterine corpus.
  • These tumors are characterized by a phyllodes-like architecture.

Purpose of the Study:

  • To report the first case of mesodermal adenosarcoma occurring in the testis.
  • To document the clinical and pathological features of this rare testicular tumor.

Main Methods:

  • Case report of a 76-year-old male patient with a testicular mass.
  • Clinical presentation, ultrasound findings, and radical orchiectomy specimen examination.
  • Microscopic evaluation and immunohistochemical analysis (muscle specific actin, CD10, desmin).

Related Experiment Videos

Main Results:

  • A 6.5-cm complex solid-cystic testicular tumor was identified.
  • Microscopic examination revealed a phyllodes-like neoplasm with benign epithelium and a malignant stromal component.
  • Immunohistochemistry showed reactivity for muscle specific actin, CD10, and desmin in the stroma.

Conclusions:

  • This case represents the first documented instance of mesodermal adenosarcoma in the testis, expanding the known anatomical sites for this tumor.
  • The findings contribute to the understanding of adenosarcoma occurrence and potential histogenesis in extragenital sites.