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Updated: Aug 9, 2026

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
Neuroendocrine carcinoma of gallbladder: report of 2 cases
Keechilat Pavithran1, Kumar Prabhash, Diganta Hazarika
1Department of Medical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, New Delhi 110085, India. drkpavithran@hotmail.com
Background:
Neuroendocrine carcinoma of the gallbladder is rare. Its best treatment is not known.
Methods:
Two patients underwent surgery earlier: one for suspected cholecystitis and the other for cholelithiasis. Magnetic resonance cholangiopancreatography (MRCP) showed residual lesions in the livers. The two patients underwent revision surgery followed by chemotherapy.
Results:
Both patients tolerated the second stage surgery well, which was followed by chemotherapy with paclitaxel, ifosphamide and cisplatin for 6 cycles. They were treated this way for 8 months and 12 months post treatment, respectively.
Conclusions:
A proper diagnosis of neuroendocrine carcinoma is made often after surgery. As it is a slow growing tumor and not very chemotherapeutically, sensitive surgery offers the best local control.
