Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertonic saline.

J E Smith1, M J Hall

  • 1Defence Medical Services. jasonsmith@doctors.org.uk

Journal of the Royal Army Medical Corps
|March 1, 2005
PubMed
Summary
This summary is machine-generated.

Hypertonic saline offers rapid volume expansion for critically ill patients, showing a trend toward increased survival. This review explores the evidence supporting its use in fluid resuscitation, especially for hypovolemic head injuries.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cellular electrophysiological effects of chronic fluoxetine and duloxetine administration on serotonergic responses in the aging hippocampus.

Synapse (New York, N.Y.)·1998
Same author

Toxoplasma gondii: an ultrastructural study of host-cell invasion by the bradyzoite stage.

Parasitology research·1998
Same author

Case management: a literature review.

Canadian journal of nursing administration·1998
Same author

The community reinforcement approach with homeless alcohol-dependent individuals.

Journal of consulting and clinical psychology·1998
Same author

CNS cell groups projecting to sympathetic outflow of tail artery: neural circuits involved in heat loss in the rat.

Brain research·1998
Same author

Training dose and session time as contextual determinants of heroin self-administration in rats.

Pharmacology, biochemistry, and behavior·1998
Same journal

A tribute to the <i>Journal of the Royal Army Medical Corps</i>.

Journal of the Royal Army Medical Corps·2019
Same journal

Towards the future: The final issue of the journal of the Royal Army Medical Corps 1903-2019.

Journal of the Royal Army Medical Corps·2019
Same journal

Interests and concerns of the Army Medical Services as reflected by the publications in the <i>Journal of the Royal Army Medical Corps</i> 1903-2019.

Journal of the Royal Army Medical Corps·2019
Same journal

Dispatched from the Editor in Chief: does the impact factor have any real relevance to our military health journal?

Journal of the Royal Army Medical Corps·2019
Same journal

Highlights of the edition: the military medical ethics special issue.

Journal of the Royal Army Medical Corps·2019
Same journal

Aeromedical evacuation in the humanitarian and disaster relief environment of Op RUMAN.

Journal of the Royal Army Medical Corps·2019
See all related articles

Area of Science:

  • Critical care medicine
  • Emergency medicine
  • Trauma resuscitation

Background:

  • The choice of resuscitation fluid for critically ill and injured patients is controversial.
  • Hypertonic saline solutions are effective for rapid volume expansion and possess favorable storage/transport characteristics.
  • Emerging evidence suggests potential survival benefits, particularly in specific patient populations.

Purpose of the Study:

  • To review the physiological and experimental evidence supporting the use of hypertonic saline in fluid resuscitation.
  • To examine the benefits of hypertonic saline in critically ill and injured patients.
  • To highlight potential advantages in specific patient groups, such as those with hypovolemic head injuries.

Main Methods:

  • Review of physiological data.

Related Experiment Videos

  • Examination of experimental evidence.
  • Analysis of recent meta-analyses on hypertonic saline use.

    • Main Results:

    • Hypertonic saline provides rapid volume expansion.
    • It has an acceptable safety profile and is convenient for storage and transport.
    • Meta-analyses indicate a trend towards improved survival rates with hypertonic saline administration.

    Conclusions:

    • Hypertonic saline is a viable option for fluid resuscitation in critically ill patients.
    • Evidence supports its use, with potential specific benefits for hypovolemic head injury.
    • Further investigation into its role in critical care is warranted.