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Updated: Aug 19, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
[Oral morphine administration for children's traumatic pain]
C Wille1, N Bocquet, B Cojocaru
1Département des urgences pédiatriques, hôpital Necker-Enfants-Malades, assistance publique-hôpitaux de Paris,149, rue de Sèvres, 75743 Paris cedex 15, France.
Insights
Oral morphine is a safe and effective pain management option for children in the pediatric emergency department (ED). This study found it simple to administer with few adverse events, providing significant pain relief within 30-60 minutes.
Area of Science:
- Pediatric Emergency Medicine
- Pain Management
- Pharmacology
Background:
- Traumatic injuries are common in children presenting to the emergency department (ED).
- Effective pain management is crucial for pediatric patients experiencing trauma.
- Oral morphine is a potential analgesic option for moderate to severe pain in children.
Purpose of the Study:
- To evaluate the adherence to prescription guidelines for oral morphine in pediatric ED.
- To assess the efficacy of oral morphine in managing traumatic pain in children.
- To identify and document adverse events associated with oral morphine use in this population.
Main Methods:
- A prospective study was conducted in a pediatric ED from October 2002 to September 2003.
- Children aged 6 months to 16 years with severe traumatic pain received oral morphine (0.5 mg/kg).
- Pain was assessed using validated scales (Faces, Objective Pain Scale, Visual Analogic Scale) at regular intervals.
Main Results:
- Seventy percent of oral morphine prescriptions followed recommended guidelines.
- Significant pain reduction was observed within 30 minutes for younger children (under 5 years).
- For older children (over 5 years), pain reduction was more rapid when assessed by nurses compared to self-reporting in the initial hour.
Conclusions:
- Oral morphine administration in the pediatric ED is straightforward and associated with a low incidence of adverse events.
- No severe adverse events were reported during the study.
- Oral morphine demonstrates effective pain relief within 30 to 60 minutes post-administration.
Objectives:
To study the compliance of prescription, the efficacity and the adverse events of oral morphine used in the pediatric emergency department (ED) in traumatic pains.
Method:
This prospective study was conducted in the ED from october 2002 to september 2003. Children aged six months to 16 years with a visual analogic scale (VAS) score higher than 70 or with a traumatic member deformation received oral morphine (0,5 mg/kg). Pain was assessed every 30 minutes using two scales: behavioral observation by the faces scale and objective pain scale (OPS) for children less than five years, behavioral observation by the faces scale and self-report by VAS for children older than five years. The compliance of prescription, the pain scores and the adverse events were studied.
Results:
Ninety-one children received oral morphine and seventy-four children were studied. Seventy per cent of prescriptions were in accordance with the recommendations. For patients younger than five years a rapid decrease of pain was observed in thirty minutes. The pain's reduction was respectively 79 and 84% with faces scale and OPS when they left ED. For children older than five years, pain's reduction was more important and more rapid when pain assessment was made by nurses than when it was self-reported in the first hour (pain reduction 58,2 and 36,1%). When leaving, pain reduction was the same with the two different assessments. No major adverse event was noted.
Conclusion:
Use of oral morphine in ED is simple, with a few numbers of adverse events. None was severe. Efficiency is correct after 30 to 60 minutes.
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