Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A case for a Glossina genome project.

Serap Aksoy1, Matt Berriman, Neil Hall

  • 1Yale University School of Medicine, 60 College Street, 606 LEPH, New Haven, CT 06520, USA. serap.aksoy@yale.edu

Trends in Parasitology
|March 1, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Apollo 3: Multi-Species Genome Curation.

bioRxiv : the preprint server for biology·2026
Same author

Canonical WNT signalling governs Echinococcus metacestode development.

PLoS pathogens·2026
Same author

Author Correction: Dietary intervention of mice using an improved Multiple Artificial-gravity Research System (MARS) under artificial 1 g.

NPJ microgravity·2026
Same author

Transcriptome profiling of intra-snail stages of the liver fluke Fasciola hepatica reveals key mediators underlying parasite development and interaction with the host.

BMC genomics·2026
Same author

The Japanese gut microbiome: ecology, uniqueness, and impact on health and disease.

Proceedings of the Japan Academy. Series B, Physical and biological sciences·2026
Same author

The effects of low-dose ketamine and (2R,6R)-Hydroxynorketamine on affective behaviors associated with protracted oxycodone withdrawal.

Psychopharmacology·2025
Same journal

Hidden diversity in Trichuris control.

Trends in parasitology·2026
Same journal

The second Cryptosporidium meeting: Edinburgh's parasite deep dive.

Trends in parasitology·2026
Same journal

Evolution of generalism under Muller's ratchet.

Trends in parasitology·2026
Same journal

Next generation in parasitology 2026: Connecting young parasitologists across Europe.

Trends in parasitology·2026
Same journal

Disrupted barriers, evolved risks: toward precision One Health in arthropod allergy.

Trends in parasitology·2026
Same journal

Unveiling malaria history using ancient genomes.

Trends in parasitology·2026
See all related articles

Researchers are preparing for a full Glossina genome sequence by generating expressed sequence tags (ESTs) and bacterial artificial chromosome (BAC) libraries. This work prioritizes understanding the vector and its pathogen interactions for medical and agricultural applications.

Area of Science:

  • Genomics
  • Vector Biology
  • Medical Entomology

Background:

  • Glossina species (tsetse flies) are medically and agriculturally significant vectors.
  • Understanding tsetse fly genomics is crucial for controlling vector-borne diseases like sleeping sickness.
  • Knowledge of vector-pathogen interactions is a high priority for effective disease management.

Purpose of the Study:

  • To lay the groundwork for a full Glossina genome sequencing initiative.
  • To generate essential genomic resources for the Glossina research community.
  • To facilitate future studies on vector biology and pathogen interactions.

Main Methods:

  • Generation of an extensive set of expressed sequence tags (ESTs) from normalized, tissue-specific libraries.
  • Construction of bacterial artificial chromosome (BAC) libraries for genomic research.

Related Experiment Videos

  • Acquisition of data on genome structure and size across different Glossina species.

    • Main Results:

    • A substantial collection of ESTs has been produced, representing a significant portion of the Glossina transcriptome.
    • BAC libraries are being developed, providing tools for large-scale genomic analysis.
    • Preliminary data on genome size and structure provide foundational information for the genome project.

    Conclusions:

    • The generated genomic resources are critical precursors for a comprehensive Glossina genome project.
    • These efforts will significantly advance the understanding of Glossina biology and its role in disease transmission.
    • An international consortium is established to support and advance the full genome sequencing efforts.