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Updated: Aug 14, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
Protein structure topological comparison, discovery and matching service
G M Torrance1, D R Gilbert, I Michalopoulos
1Bioinformatics Research Centre, Department of Computer Science, University of Glasgow, Glasgow G12 8QQ, UK.
Unlabelled:
We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain.
Availability:
Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites.
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