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The influence of calcium on the ototoxicity of aminoglycosides
1Klinik für Hals-, Nasen- und Ohrenkrankheiten, Dominikus Krankenhaus, Düsseldorf, Germany.
Acta Oto-Laryngologica
|January 1, 1992
Abstract:
Aminoglycosides in aquarium water produce a temporary impairment of sensitivity in the lateral line organ of fish. If Ca++ ions are supplied at the same time, the impairment in lateral line sensitivity can be alleviated in a dose-dependent manner. This mechanism appears to be based on competitive antagonism.