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Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica
Published on: October 28, 2022
Comparative study of lung function in Iranian factory workers exposed to silica dust
1Department of Occupational Health, Hamadan University of Medical Science, Hamadan, Islamic Republic of Iran.
Abstract:
The study compared lung function among 322 workers in pottery, ceramic, stone-cutter and stone-grinder factories in the west of the Islamic Republic of Iran. Concentrations of silica particles <2 microm were measured in the ambient air of factories. Forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) were significantly lower in stone-grinders compared with pottery, ceramic or stone-cutter workers and a control group. No difference in lung function was found in pottery and stone-cutter workers with less than 20 years occupation compared with controls. The prevalence of respiratory symptoms in stone-grinders was higher than other workers. The concentration of silica particles of stone-grinder factories was 40-110 times higher than in ceramic and potteries factories. More attention is needed to ventilation systems and health care of stone-grinders.

