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Related Experiment Videos

Ultraviolet-free phototherapy.

Jean Krutmann1, Kathrin Medve-Koenigs, Thomas Ruzicka

  • 1Environmental Health Research Institute, Heinrich-Heine-University of Düsseldorf GmbH, Germany. krutmann@rz.uni-duesseldorf.de

Photodermatology, Photoimmunology & Photomedicine
|March 9, 2005
PubMed
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This study shows that UV-free light therapy effectively treats atopic hand and foot eczema. Visible light irradiation significantly improved eczema symptoms, offering a safer alternative to traditional UV phototherapy.

Area of Science:

  • Dermatology
  • Phototherapy
  • Medical Devices

Background:

  • Ultraviolet (UV) radiation phototherapy is a long-standing treatment for skin conditions.
  • UV radiation is a known carcinogen, limiting its use in certain patient groups and long-term management.
  • Concerns about UV carcinogenicity necessitate exploring alternative treatment modalities.

Purpose of the Study:

  • To evaluate the efficacy of a novel UV-free irradiation device for treating atopic hand and/or foot eczema.
  • To assess the therapeutic potential of visible light in managing eczema.

Main Methods:

  • A single-blinded trial involving 10 patients with atopic hand and/or foot eczema.
  • Patients received treatment with a UV-free device (DermoDyne) and a sham device over 4 weeks.

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  • Treatments were administered three times weekly for 30 minutes per session.

    • Main Results:

    • UV-free irradiation resulted in significant clinical improvement of atopic hand and foot eczema (P = 0.0001).
    • Sham irradiation showed no significant effect on eczema symptoms (P = 0.39).
    • The results indicate a clear benefit of the UV-free device.

    Conclusions:

    • Visible light irradiation is a viable and effective treatment for atopic eczema.
    • The developed UV-free device demonstrates therapeutic potential for eczema management.
    • This approach offers a safer alternative to UV phototherapy for certain patient populations.