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Reversible nocturnal enuresis in children receiving SSRI with or without risperidone: presentation of five cases

Sema Tanriover Kandil1, Hatice Bagdatli Aksu, Rasin Ozyavuz

  • 1Department of Child Psychiatry, Karadeniz Technical University Medical School, Trabzon, Turkey. stkandil@meds.ktu.edu.tr

The Israel Journal of Psychiatry and Related Sciences
|March 10, 2005
PubMed

Insights

Selective serotonin re-uptake inhibitors (SSRIs) can cause bed-wetting in children, even when used for enuresis. This study highlights a potential side effect of SSRIs and risperidone in pediatric patients.

Area of Science:

  • Pediatric Psychiatry
  • Pharmacology

Background:

  • Selective serotonin re-uptake inhibitors (SSRIs) are commonly prescribed for childhood psychiatric disorders.
  • Existing data suggest SSRIs may be used in enuresis treatment.
  • Voiding dysfunction has been anecdotally linked to SSRI use.

Observation:

  • Five pediatric patients developed new-onset enuresis (bed-wetting).
  • Patients were undergoing treatment with an SSRI, with or without risperidone.
  • The enuresis emerged during the course of this psychiatric medication regimen.

Findings:

  • Bed-wetting emerged as a potential adverse effect in children treated with SSRIs.
  • The co-administration of risperidone did not preclude this side effect.
  • This observation suggests a possible link between SSRIs and acquired enuresis.

Implications:

  • Clinicians should be aware of acquired enuresis as a potential SSRI side effect in pediatric populations.
  • Further investigation into the mechanism of SSRI-induced enuresis is warranted.
  • This finding may inform treatment decisions and patient counseling regarding SSRIs in children.

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