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Updated: Aug 19, 2026

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
Published on: November 30, 2021
Ancient DNA analysis of human neolithic remains found in northeastern Siberia
François-Xavier Ricaut1, A Fedoseeva, Christine Keyser-Tracqui
1Laboratoire d'Anthropologie Moléculaire, Institut de Médecine Légale, 67085 Strasbourg, France. fx.ricaut@infonie.fr
Abstract:
We successfully extracted DNA from a bone sample of a Neolithic skeleton (dated 3,600 +/- 60 years BP) excavated in northeastern Yakutia (east Siberia). Ancient DNA was analyzed by autosomal STRs (short tandem repeats) and by sequencing of the hypervariable region I (HV1) of the mitochondrial DNA (mtDNA) control region. The STR profile, the mitochondrial haplotype, and the haplogroup determined were compared with those of modern Eurasian and Native American populations. The results showed the affinity of this ancient skeleton with both east Siberian/Asian and Native American populations.
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