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Does fibrin sealant decrease immediate urinary leakage following radical retropubic prostatectomy?
Eric K Diner1, Sunil V Patel, Arnold M Kwart
1Department of Urology, Washington Hospital Center, Washington, DC 20010, USA. ericdiner@hotmail.com
The Journal of Urology
|March 11, 2005
Summary
Fibrin sealant significantly reduced urinary leakage after radical retropubic prostatectomy, leading to earlier drain removal. This application improves patient comfort and may expedite hospital discharge.
Area of Science:
- Urology
- Surgical Innovation
- Medical Devices
Background:
- Radical retropubic prostatectomy is a common procedure for prostate cancer.
- Postoperative urinary leakage can complicate recovery.
- Minimizing drain output is crucial for patient comfort and early discharge.
Purpose of the Study:
- To evaluate the effectiveness of fibrin sealant in reducing urinary leakage after radical retropubic prostatectomy.
- To assess the impact of fibrin sealant on postoperative drain output and drain removal timing.
Main Methods:
- A comparative study of 32 patients undergoing radical retropubic prostatectomy.
- 16 patients received standard technique (control group).
- 16 patients received fibrin sealant applied to the urethrovesical anastomosis.
Main Results:
- The fibrin sealant group showed significantly less overall drain output (p = 0.005).
- Earlier drain removal was achieved in 100% of the fibrin sealant group versus 81% of the control group.
- No immediate adverse events were associated with fibrin sealant use.
Conclusions:
- Fibrin sealant effectively decreases postoperative drain output following radical retropubic prostatectomy.
- Early drain removal, facilitated by fibrin sealant, can enhance patient comfort and potentially shorten hospital stays.
- Fibrin sealant is a safe adjunct for reducing urinary leakage in prostatectomy patients.