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Updated: Jun 21, 2026

An Enzymatic Method to Rescue Mesenchymal Stem Cells from Clotted Bone Marrow Samples
Published on: April 12, 2015
[Plasticity and application of marrow-derived stem cells]
Xiaojun Duan1, Yue Zhou, Liu Yang
1Department of Orthopedic Surgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038, PR China.
Objective:
To investigate plasticity of marrow-derived stem cells, possible mechanisms and application.
Methods:
The recent literature concerned plasticity of marrow-derived stem cells was extensively reviewed.
Results:
Although stem cells plasticity has not been proven, there is more and more evidence to show that the stem cells may have the plasticity and at least four different mechanisms are explained.
Conclusion:
The extensive research will be required. If the plasticity is proven, adult stem cells can be used for more therapeutic purposes. For example, the use of stem cells from bone marrow may correct genetic or degenerative disorders of a second organ from which stem cells are more difficult to isolate.
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