Related Experiment Videos
Pemphigus vegetans occurring in a split-thickness skin graft.
Yu-Huei Huang1, Shu-Hui Wang, Tseng-Tong Kuo
1Department of Dermatology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Summary
Pemphigus vegetans, a rare variant of pemphigus vulgaris, presented unusually in a skin graft recipient site. This case highlights the importance of considering this autoimmune blistering disease in graft sites.
Area of Science:
- Dermatology
- Autoimmune Blistering Diseases
Background:
- Pemphigus vegetans is a rare variant of pemphigus vulgaris.
- Typically presents in flexural areas.
Observation:
- A 41-year-old male developed vegetating plaques at a split-thickness skin graft recipient site on his left leg over 8 months.
- This presentation is atypical for pemphigus vegetans.
Findings:
- Histopathologic examination of a skin biopsy confirmed the diagnosis of pemphigus vegetans.
- The patient responded well to treatment with systemic corticosteroids and acitretin.
Implications:
- This case is unique due to the occurrence of pemphigus vegetans shortly after a skin graft.
- Clinicians must consider pemphigus vegetans when evaluating cutaneous lesions on skin graft sites.