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Updated: Aug 17, 2026
Immunolabeling and Counting Ribbon Synapses in Young Adult and Aged Gerbil Cochleae
Published on: April 21, 2022
[Lipid profile and hearing-loss aged-related]
C Martín Villares1, J San Román Carbajo, J Domínguez Calvo
1Servicio de ORL, Hospital de El Bierzo, Ponferrada, León. cmvillares@hotmail.com
Objectives/Hypothesis:
Presbycusis is the most prevalent cause of hearing-loss in the older, but pathogenesis is not well-know. The premise of this study is that hyperlipemia increase risk of age-related hearing-loss.
Patients And Methods:
180 patient more than 65 years-old were studied. All patients had bilateral hearing-loss and no renal, neurological, thyriod or middle-ear pathology. We explored serum levels of cholesterol, HDL, LDL and triglycerides. We performed tonal audimetry in all patients.
Results:
The 71% of patients has hypercholesteremia and the highest serum levels were detected in 65-69 years-old men (mean media 5,27). Patients with hypercholesteremia had worse hearing-loss than patients with normal lipid serum levels (p < .05).
Conclusions:
Our study sugest that hypercholesteremia are associated to age-related hearing-loss, possibly by an atherosclerosis mechanism.
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