Related Experiment Video

Updated: Jul 14, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
06:09

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

[Cutaneous melanoma of the head and neck]

P Pomar Blanco1, J San Román Carbajo, C Martín Villares

  • 1Servicio de ORL, Facultativo Especialista de Otorrinolaringología, Hospital Del Bierzo, Ponferrada, León. pilipomar@hotmail.com

Anales Otorrinolaringologicos Ibero-Americanos
|June 7, 2007
PubMed

Insights

This study reviewed 20 head and neck cutaneous melanoma cases treated from 1991-2005. Advances in diagnosis and treatment significantly impact patient outcomes for this skin cancer.

Area of Science:

  • Oncology
  • Dermatology
  • Surgical Pathology

Context:

  • Retrospective review of 20 head and neck cutaneous melanoma cases treated between 1991 and 2005.
  • Highlights the evolution of diagnostic techniques and therapeutic strategies in melanoma management.
  • Focuses on the specific challenges and treatment paradigms for head and neck melanomas.

Purpose:

  • To evaluate the impact of advancements in diagnostic techniques and treatment on outcomes for cutaneous melanoma.
  • To describe the standard treatment protocols for early and advanced stage cutaneous melanoma of the head and neck.
  • To outline the necessity of staging evaluations and potential adjuvant therapies.

Summary:

  • Cutaneous melanoma of the head and neck requires complete surgical resection, with margins dictated by tumor size and depth.
  • Advanced stages necessitate evaluation for regional and distant metastasis.
  • Adjuvant therapy may be considered for cases involving regional lymph nodes.

Impact:

  • Demonstrates the significant influence of improved diagnostics and treatments on melanoma patient outcomes.
  • Provides insights into the surgical management and staging of head and neck melanomas.
  • Underscores the importance of tailored treatment strategies based on disease stage and extent.

More Related Videos

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma08:59

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Published on: January 5, 2017

A 3D Organotypic Melanoma Spheroid Skin Model08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...