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Updated: Jul 7, 2026

04:04
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Published on: August 15, 2025
[Facial mutilant basosquamous carcinoma]
F J Rodríguez-Domínguez1, J Hernández-Gil, J D Segarra Fenoll
1Hospital Santa María del Rosell, Cartagena, Murcia. franrodrguez@yahoo.es
Summary
Basosquamous carcinoma, a rare cancer, presents aggressive features of basal and squamous cell types. Early detection and removal are crucial due to high recurrence and metastatic potential.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Basosquamous carcinoma is a rare malignant neoplasm.
- It exhibits features of both basal cell carcinoma and squamous cell carcinoma.
- Previously considered a variant, it's now recognized as a distinct clinical entity.
Observation:
- A case report of a 59-year-old homeless male patient is presented.
- The patient had an ulcerated tumoral lesion on the left malar region, orbit, and nasal pyramid for four years.
- The lesion caused significant destruction of these structures and spread to the skull base via the optic nerve.
Findings:
- Basosquamous carcinoma is characterized by significant local aggressiveness.
- This neoplasm demonstrates a high frequency of recurrence.
- It possesses a notable metastatic potential.
Implications:
- Early detection and complete surgical removal are the most effective therapeutic strategies.
- The aggressive nature of basosquamous carcinoma can make complete tumor removal challenging, as illustrated by the case.
- Understanding its aggressive behavior is vital for patient management and treatment planning.
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