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Updated: Aug 19, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
S-nitrosothiol and S-nitrosoalbumin levels in pre-eclampsia plasma
1Department of Obstetrics and Gynaecology, and MRC/UN Pregnancy Hypertension Research Unit, University of Natal, Congella 4013, South Africa. gynae@nu.ac.za
Abstract:
The aetiology of pre-eclampsia still eludes researchers. Recently, the development of laboratory techniques to measure the levels of serum nitrosothiols, compounds that appear to play a role in signal transduction and stress responses, could be the driving force in the search for the exact cause of pre-eclampsia. We attempted to verify a new technique of estimating the levels of S-nitrosothiols and S-nitrosoalbumin in pre-eclampsia. The laboratory technique used as described previously could not identify these compounds. None the less, these nitrosothiols and nitrosoalbumin may be involved in the aetiology of pre-eclampsia.
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