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Updated: Aug 19, 2026

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
Relationship between age and tibial plateau angle in dogs with cranial cruciate rupture
Philippe A Zeltzman1, Bernard Paré, Gretchen M Johnson
1Surgical Referral Service, Buffalo Grove, Illinois 60089, USA.
Abstract:
The pathogenesis of cranial cruciate ligament (CCL) rupture remains controversial, and its relationship to tibial plateau angle is unknown. In this study, the tibial plateau angle was measured in 200 large-breed dogs diagnosed with CCL rupture. Correlation analyses were performed to determine whether the age at the time of CCL rupture and the tibial plateau angle were related. While these two values were inversely correlated, the relationship was not strong enough to explain the frequency of CCL rupture in young, large-breed dogs. There was no statistically significant correlation between age at the time of CCL rupture and tibial plateau angle.
