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MR findings in eosinophilic infiltration of the liver
Joo Sung Sun1, Jai Keun Kim, Je Hwan Won
1Department of Diagnostic Radiology, Ajou University, College of Medicine, Kyunggido, Korea.
Objective:
This study describes the findings of magnetic resonance imaging (MRI) of focal eosinophilic infiltration of the liver.
Methods:
Contrast-enhanced MR images of 8 patients with focal hepatic eosinophilic infiltration were reviewed retrospectively. We evaluated the signal intensity of focal lesions in T1-weighted and T2-weighted images and the pattern of enhancement in a dynamic contrast study.
Results:
A total 22 focal hepatic lesions were observed; the lesions were isointense (55%) or hypointense (45%) on T1-weighted images and isointense (14%) or hyperintense (86%) on T2-weighted images. The arterial phase of the contrast study revealed 11 hyperintense lesions (50%). During the portal and delayed phases, 18 (82%) and 17 lesions (77%) were hyperintense, respectively.
Conclusion:
The focal eosinophilic infiltrations showed homogeneous enhancement in the portal and delayed phases in the dynamic contrast MR study. These findings should help to distinguish focal eosinophilic infiltration, especially from metastasis in patients with malignancy.
Insights
Magnetic resonance imaging (MRI) reveals characteristic patterns of focal hepatic eosinophilic infiltration. These findings aid in differentiating this condition from malignant liver tumors.
Area of Science:
- Hepatology
- Radiology
- Medical Imaging
Background:
- Focal eosinophilic infiltration of the liver is a rare condition.
- Accurate diagnosis is crucial for appropriate management.
- Distinguishing it from other liver lesions, particularly malignancy, can be challenging.
Purpose of the Study:
- To describe the magnetic resonance imaging (MRI) findings of focal eosinophilic infiltration of the liver.
- To evaluate the utility of contrast-enhanced MRI in characterizing these lesions.
- To assist in differentiating focal eosinophilic infiltration from other liver pathologies.
Main Methods:
- Retrospective review of contrast-enhanced MRI scans from 8 patients.
- Analysis of signal intensity on T1-weighted and T2-weighted images.
- Evaluation of dynamic contrast enhancement patterns.
Main Results:
- 22 focal hepatic lesions were identified.
- Lesions were typically isointense to hypointense on T1-weighted images (55% isointense, 45% hypointense).
- Lesions were predominantly hyperintense on T2-weighted images (86%).
- Homogeneous enhancement was observed in the portal (82%) and delayed (77%) phases after contrast administration.
Conclusions:
- Focal eosinophilic infiltrations demonstrate characteristic homogeneous enhancement in portal and delayed phases on dynamic contrast-enhanced MRI.
- These MRI features can help differentiate focal eosinophilic infiltration from liver metastases in patients with a history of malignancy.
