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Related Experiment Videos

Allergic fungal sinusitis.

L A Schwietz1, D S Gourley

  • 1Wilford Hall Medical Center, SGHMMA, Lackland Airforce Base, TX 78236-5300.

Allergy Proceedings : the Official Journal of Regional and State Allergy Societies
|January 1, 1992
PubMed
Summary
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Allergic fungal sinusitis (AFS) is a noninvasive condition affecting atopic individuals with chronic sinusitis and nasal polyps. Early diagnosis and treatment are crucial as AFS often requires surgery and can relapse.

Area of Science:

  • Otolaryngology
  • Allergy and Immunology

Background:

  • Allergic fungal sinusitis (AFS) is a noninvasive condition characterized by fungal debris and eosinophilic mucin.
  • It typically affects immunocompetent, atopic patients with chronic sinusitis refractory to medical treatment, often presenting with nasal polyps.

Purpose of the Study:

  • To review the clinical and histopathologic features of Allergic fungal sinusitis (AFS).
  • To emphasize the diagnostic considerations for AFS in atopic patients with nasal polyps and chronic sinusitis.

Main Methods:

  • Review of clinical and histopathologic features of Allergic fungal sinusitis (AFS).
  • Analysis of patient demographics, symptoms, and treatment outcomes.

Main Results:

  • Allergic fungal sinusitis (AFS) occurs in 7% of chronic sinusitis patients requiring surgery.

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  • Nasal polyps are present in 100% of diagnosed AFS cases.
  • Relapse is common after surgical debridement and often responds to systemic corticosteroids.

    • Conclusions:

    • Allergic fungal sinusitis (AFS) diagnosis should be considered in atopic patients with nasal polyps and chronic sinusitis.
    • Understanding the distinct clinical and histopathologic features is essential for accurate diagnosis and management.