Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Predictive factors for bone loss].

Noriko Yoshimura1

  • 1Department of Public Health, Wakayama Medical University School of Medicine.

Clinical Calcium
|March 19, 2005
PubMed
Summary

Understanding bone loss is key for osteoporosis prevention. Aging, female sex, and weight changes significantly predict bone density decline, while metabolic markers are poor predictors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence and Radiographic Progression of Rheumatoid Arthritis in Anti-Citrullinated Protein Antibody-Positive Individuals: A Six-Year Population- Based Cohort Study.

Modern rheumatology·2026
Same author

New insights into spinopelvic-hip motion age-related changes in postural adaptability.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association·2026
Same author

Impact of Unfractionated Heparin Use on Maternal Bone Mineral Density During Pregnancy: A Retrospective Study Using AI-Assisted Radiographic Analysis.

Reproductive sciences (Thousand Oaks, Calif.)·2026
Same author

Overlap syndrome between sarcoidosis and Sjögren's disease presenting as hypopituitarism: case report and review of literature.

Endocrine journal·2026
Same author

Functional Resilience in Chronic Low Back Pain: Dissociating Magnetic Resonance Imaging Abnormalities From Real-World Disability in the Wakayama Spine Study.

Neurospine·2026
Same author

Towards efficient osteoporosis screening: a simple and practical approach using OSTA and FRAX risk factors.

Journal of bone and mineral metabolism·2026

Area of Science:

  • Gerontology
  • Endocrinology
  • Bone Biology

Context:

  • Osteoporosis prevention requires understanding age-related bone loss patterns.
  • Longitudinal studies on bone mineral density (BMD) in the general population are scarce.
  • Identifying predictors of bone loss is crucial for developing effective preventive strategies.

Purpose:

  • To characterize determinants of bone loss in later life.
  • To assess the predictive capability of identified determinants for future bone loss.
  • To evaluate the role of bone metabolic markers in predicting BMD changes.

Summary:

  • Aging, female sex, and the perimenopausal period significantly correlate with accelerated bone loss.
  • Baseline anthropometric measurements, including weight, height, and BMI, are significant predictors of BMD changes.
  • Bone metabolic markers show limited predictive power (less than 10% determination) for individual BMD changes, suggesting the need for additional factors.

Impact:

  • Highlights significant generation gaps in bone density between current and past cohorts, particularly in men in their 60s and women in their 50s.
  • Suggests that current bone metabolic markers are insufficient for predicting individual bone loss.
  • Emphasizes the need to incorporate novel biochemical markers and lifestyle factors into clinical assessments for better osteoporosis risk prediction.

Related Experiment Videos