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Updated: Aug 19, 2026

An Optimized O9-1/Hydrogel System for Studying Mechanical Signals in Neural Crest Cells
11:02

An Optimized O9-1/Hydrogel System for Studying Mechanical Signals in Neural Crest Cells

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[Osteoclasts and alphavbeta3 integrin]

Ichiro Nakamura1

  • 1Department of Orthopaedic Surgery, Yugawara kosei-nenkin Hosipital.

Clinical Calcium
|March 19, 2005
PubMed

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Activation of Integrins

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Intracellular Signaling Affects Focal Adhesions

Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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Immunoglobulin-like Cell Adhesion Molecules

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