Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gallbladder cancer presenting with acute cholecystitis: a population-based study.

C M Lam1, A W Yuen, A C Wai

  • 1Central Surgical Audit Unit, Hospital Authority, Hospital Authority Building, 147 B Argyle Street, Kowloon, Hong Kong. lamcm@hkucc.hku.hk <lamcm@hkucc.hku.hk>

Surgical Endoscopy
|March 19, 2005
PubMed
Summary

Gallbladder cancer incidence is higher in acute cholecystitis patients in Hong Kong. Early diagnosis during acute cholecystitis may allow for long-term survival, even with laparoscopic cholecystectomy (LC).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-omic spatial effects on high-resolution AI-derived retinal thickness.

Nature communications·2025
Same author

2024 Hong Kong College of Obstetricians and Gynaecologists Guidelines for cervical cancer prevention and screening.

Hong Kong medical journal = Xianggang yi xue za zhi·2024
Same author

Multimodal Biomarkers That Predict the Presence of Gleason Pattern 4: Potential Impact for Active Surveillance.

The Journal of urology·2023
Same author

Protective Effect of Bojungikki-Tang against Radiation-Induced Intestinal Injury in Mice: Experimental Verification and Compound-Target Prediction.

Evidence-based complementary and alternative medicine : eCAM·2023
Same author

Simple instrument for ascending urethrography in males.

The Medical journal of Malaysia·2022
Same author

Multimodality imaging of developmental splenic anomalies: tips and pitfalls.

Clinical radiology·2022

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Hepatobiliary Surgery

Background:

  • The role of laparoscopic cholecystectomy (LC) in acute cholecystitis is debated.
  • Gallbladder cancer (GC) diagnosis often occurs incidentally during cholecystectomy for gallstones.
  • Acute cholecystitis may present a unique window for GC detection.

Purpose of the Study:

  • To determine the incidence and clinicopathological characteristics of gallbladder cancer in patients presenting with acute cholecystitis.
  • To evaluate the outcomes of patients with gallbladder cancer diagnosed during acute cholecystitis, including those treated with LC.
  • To compare outcomes between open and laparoscopic cholecystectomy for acute cholecystitis with incidental gallbladder cancer.

Main Methods:

  • Retrospective analysis of patients with gallbladder cancer presenting with acute cholecystitis.

Related Experiment Videos

  • Data collected from public hospitals in Hong Kong between 1998 and 2002.
  • Comparison of outcomes (complications, mortality, survival) between open and LC groups.

    • Main Results:

    • 63 of 2,700 (2.3%) patients with acute cholecystitis had gallbladder cancer.
    • Adenocarcinoma was the most common type (90.5%). Median survival was 5 months; 5-year survival was 20.8%.
    • LC was attempted in 11 patients (6 successful) with no significant difference in outcomes compared to open surgery.

    Conclusions:

    • The incidence of gallbladder cancer presenting with acute cholecystitis is higher in Hong Kong's ethnic Chinese population compared to elective cases.
    • Early diagnosis of gallbladder cancer during acute cholecystitis is possible.
    • Long-term survival is achievable, suggesting potential for early-stage detection and treatment.