Related Experiment Video
Updated: Aug 19, 2026

Generation and Genetic Manipulation of Human Cervical Organoids
Published on: March 10, 2026
A five century evolution of cervical incompetence as a clinical entity
1Department of Obstetrics and Gynecology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands. divedoc@xs4all.nl
Abstract:
Since cervical incompetence was introduced in the English literature in 1678, our understanding and obstetric management of this clinical entity, have changed tremendously over the years. This review shows the historical perspective of the development of cervical incompetence as a distinct clinical entity and an all or nothing phenomenon to cervical incompetence as part of a spectrum leading to preterm delivery, which can express differently in subsequent pregnancies. These changes in our understanding imply consequences for the obstetric management of cervical incompetence. This review focuses on the obstetric management of women considered to be at high risk of preterm delivery due to cervical incompetence, by transvaginal ultrasonographic follow-up of cervical length and transvaginal cervical cerclage.
Related Concept Videos
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Secondary Spinal Cord Injury llI: Pathophysiology
Herniated Intervertebral Disc l: Introduction