Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

High-resolution diffusion-weighted imaging with interleaved variable-density spiral acquisitions.

Tie-Qiang Li1, Dong-Hyun Kim, Michael E Moseley

  • 1Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disease and Stroke, National Institute of Health, Bethesda, Maryland 20892, USA. litie@ninds.nih.gov

Journal of Magnetic Resonance Imaging : JMRI
|March 22, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeted fluorescent magnetic nanoparticles for imaging of human breast cancer.

International journal of clinical and experimental medicine·2015
Same author

Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template.

Antiviral research·2015
Same author

Combined lateral femoral epicondylar osteotomy and a submeniscal approach for the treatment of a tibial plateau fracture involving the posterolateral quadrant.

Injury·2014
Same author

Effects of a continuous electromagnetic field on wound healing in human airway.

The Laryngoscope·2014
Same author

Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on trypanosoma brucei by forming an adduct with trypanothione.

Molecular pharmacology·2014
Same author

Kinetic variations between reverse transcriptases of viral protein X coding and noncoding lentiviruses.

Retrovirology·2014
Same journal

Editorial for "Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Association of Iron and Myelin Alterations in the Contralesional Dentate Nucleus and Thalamus With Functional Outcome in Acute Ischemic Stroke: A Susceptibility Source Separation Study.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

A Quantitative Modification of VI-RADS for Bladder Cancer at the Ureteral Orifice: A Reader Study on MRI With Varying Experience Levels.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Editorial for "Integrating nnU-Net Segmentation and Clinical-Radiomics for Multicenter Prediction of Soft Tissue Sarcoma Grade and Ki-67 Expression".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Structural MRI Volumetry Index for Differentiation of Progressive Supranuclear Palsy From Parkinson's Disease and Multiple System Atrophy by Automatic Segmentation: A Comparison With Magnetic Resonance Parkinsonism Index.

Journal of magnetic resonance imaging : JMRI·2026
See all related articles

This study introduces a new magnetic resonance imaging (MRI) technique for high-resolution brain diffusion-weighted imaging (DWI). The method achieves accurate apparent diffusion coefficient (ADC) measurements, offering a time-efficient approach for clinical use.

Area of Science:

  • Medical Imaging
  • Neuroimaging
  • Diffusion-Weighted Imaging

Background:

  • High-resolution diffusion-weighted imaging (DWI) is crucial for brain analysis.
  • Traditional DWI methods face challenges with resolution and acquisition time.

Purpose of the Study:

  • To develop a multishot MRI pulse sequence and reconstruction algorithm for submillimeter in-plane resolution brain DWI.
  • To enable time-efficient, high-quality DWI acquisition on clinical scanners.

Main Methods:

  • Implemented a self-navigated multishot acquisition using variable-density spiral k-space trajectories.
  • Developed a reconstruction algorithm leveraging central k-space oversampling for imaging and motion correction.
  • Tested the technique in phantoms and healthy volunteers.

Related Experiment Videos

Main Results:

  • Achieved submillimeter in-plane resolution (0.9 x 0.9 mm²) DWI with motion correction.
  • Obtained accurate apparent diffusion coefficient (ADC) values in phantoms and healthy adult brains.
  • Demonstrated successful acquisition with 8-32 interleaves.

Conclusions:

  • The developed self-navigated multishot spiral DWI is time-efficient for clinical scanners.
  • The k-space motion correction algorithm is robust.
  • The technique yields accurate and reproducible ADC values for high-resolution brain imaging.