The perioperative management of a patient with complex single ventricle physiology and pheochromocytoma
Related Experiment Video
Updated: Aug 19, 2026

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
J William Sparks1, Christian Seefelder, Robert C Shamberger
1*Division of Perioperative Medicine and †Division of Cardiac Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, and ‡Department of Surgery, Children's Hospital and Harvard Medical School, Boston, Massachusetts.
Abstract:
Pheochromocytoma is associated with intense physiologic effects of alpha- and beta-adrenergic stimulation from catecholamine secretion. Perioperative management for these patients includes alpha-adrenergic receptor blockade, intravascular volume replacement, and, if necessary, beta-adrenergic receptor blockade. Significant perioperative changes in preload and afterload, fluid status, heart rate and rhythm, and inotropy can occur and may be contrary to anesthetic management goals for patients with certain conditions of congenital heart disease. We report the perioperative management with doxazosin of a patient with single ventricle physiology and cavo-pulmonary and aorto-pulmonary lung perfusion who presented for resection of a pheochromocytoma.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiopulmonary Resuscitation IV: Pharmacological Management
Aneurysm IV: Nursing Management
Dysrhythmias VI: Management of Dysrhythmias
Cardiomyopathy V: Interprofessional Care
Cardiac Catheterization IV: Nursing Management