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Updated: Aug 18, 2026

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Published on: March 8, 2024
Tryptamine-derived amides and alkaloids from the seeds of Annona atemoya
Yang-Chang Wu1, Fang-Rong Chang, Chung-Yi Chen
1Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China. yachwu@kmu.edu.tw
Abstract:
A series of N-fatty acyl tryptamines, including a mixture of N-nonadecanoyltryptamine (1), N-behenoyltryptamine (2), N-lignoceroyltryptamine (3), N-cerotoyltryptamine (4), and N-octacosanoyl tryptamine (5), and a mixture of N-tricosanoyl-4,5-dihydroxytryptamine (6), N-lignoceroyl-4,5-dihydroxytryptamine (7), N-pentacosanoyl-4,5-dihydroxytryptamine (8), and N-heptacosanoyl-4,5-dihydroxytryptamine (9), along with two alkaloids, atemoine (10) and cleistopholine, were isolated from the EtOAc extract of seeds of Annona atemoya. The structures of the new compounds, 1 and 5-10, were determined on the basis of spectral evidence.
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