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Low-dose CT colonography in children: initial experience, technical feasibility, and utility
Sudha Anupindi1, James Perumpillichira, Diego Jaramillo
1Department of Radiology, Massachusetts General Hospital, 55 Fruit St., White 246, Boston, MA 02115, USA. sanupindi@partners.org
Background:
CT colonography (CTC) is utilized as a diagnostic tool in the detection of colon polyps and early colorectal cancer in adults. Large studies in the literature, although focused on adult populations, have shown CTC to be a safe, accurate, non-invasive technique.
Objective:
We evaluated the technical feasibility of CTC in children using a low-dose technique.
Materials And Methods:
From November 2001 to April 2004 we evaluated eight patients (3-17 years) with non-contrast CTC. Seven of the patients had CTC, followed by standard colonoscopy (SC) the same day; in one patient, CTC followed a failed SC. CTC results were compared to results of SC. The estimated effective dose from each CTC was calculated and compared to that of standard barium enema.
Results:
CTC results were consistent with those of SC. Sensitivity for polyps 5-10 mm was 100%, and sensitivity for polyps 10 mm and larger was 66.7%. The estimated mean effective dose was 2.17 mSv for CTC, compared to the 5-6 mSv for a standard air-contrast barium enema in a small child.
Conclusion:
Our initial experience shows CTC in children is well-tolerated, safe, and useful. The procedure can be performed successfully with a low radiation dose, and preliminary results compare well with SC.
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